На X- и Y-хромосомах человека существуют псевдоаут...

Analyzing genetics problem

This is a tricky genetics word problem in Russian! The key part is figuring out the parental genotypes and whether it's possible for them to have a child with both diseases: skeletal abnormality (involving PAR regions on X and Y) and night blindness (X-linked recessive allele).
The skeletal disorder gene seems to be in the PAR, where crossing over happens, but I'm unsure if it's dominant or recessive. On the other hand, the night blindness gene is X-linked and recessive. I’ll need to determine all possible combinations.

Analyzing inheritance patterns

Alright, let's break this down. A woman with skeletal disorder and night blindness marries a man without either disease, but his mother had a skeletal disorder. That suggests the woman’s skeletal disorder gene could be recessive or she’s heterozygous due to special inheritance from both X and Y. The skeletal disorder allele could be dominant, and I’m guessing from the pedigree analysis that the father's X/Y genes might play into it. We also need to evaluate how the pseudoautosomal gene behaves, factoring in potential dominance.

Analyzing genetic inheritance

For the skeletal disorder, I’m testing whether it's recessive or dominant. The woman’s parents are unaffected, but she has the disorder, which fits a recessive inheritance. Her husband has an affected mother, so he’s likely a carrier. The gene for the disorder could be in the pseudoautosomal region, with potential crossover during meiosis. The woman has both skeletal disorder and night blindness. The husband is unaffected, so his genotype is likely X^s Y^S for skeletal genes and wild-type for night blindness. I need to explore the offspring possibilities next.

Tracking inheritance patterns

The mother always delivers X^s, and the father's gametes, depending on recombination, have combinations like X^s, X^S, or Y^S. Their offspring possibilities include both males and females with various genotypes, like heterozygous carriers (X^s X^S for skeleton) or affected males (X^s Y^s for both diseases). In the second marriage, the unaffected daughter could pass on genes like X^S, X^s, and X^A, making her a possible carrier for both the skeletal and night blindness genes. We need to analyze offspring from this pair's crossing.

Thought for 1m 16s